0000950142-01-500515.txt : 20011107 0000950142-01-500515.hdr.sgml : 20011107 ACCESSION NUMBER: 0000950142-01-500515 CONFORMED SUBMISSION TYPE: SC 13D/A PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 20011102 GROUP MEMBERS: FRANK H. PEARL GROUP MEMBERS: GEORGE SOROS GROUP MEMBERS: PERSEUS CAPITAL, LLC GROUP MEMBERS: PERSEUS MANAGEMENT, LLC GROUP MEMBERS: PERSEUS, LLC GROUP MEMBERS: PSV GP, LLC GROUP MEMBERS: PSV PARTNERS, LLC GROUP MEMBERS: PSV, LP GROUP MEMBERS: RAPPAHANNOCK INVESTMENT CO GROUP MEMBERS: SFM AH, INC. GROUP MEMBERS: SFM PARTICIPATION, L.P. GROUP MEMBERS: SOROS FUND MANAGEMENT, LLC SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: VIROPHARMA INC CENTRAL INDEX KEY: 0000946840 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 232789550 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A SEC ACT: 1934 Act SEC FILE NUMBER: 005-48239 FILM NUMBER: 1774208 BUSINESS ADDRESS: STREET 1: 405 EAGLEVIEW BLVD STREET 2: PO BOX 5000 CITY: EXTON STATE: PA ZIP: 19341 BUSINESS PHONE: 6104587300 MAIL ADDRESS: STREET 1: 76 GREAT VALLEY PARKWAY CITY: MALVERN STATE: PA ZIP: 19355 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: SOROS GEORGE CENTRAL INDEX KEY: 0000900203 STANDARD INDUSTRIAL CLASSIFICATION: UNKNOWN SIC - 0000 [0000] STATE OF INCORPORATION: NY FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13D/A BUSINESS ADDRESS: STREET 1: 888 SEVENTH AVENUE STREET 2: 33RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10106 BUSINESS PHONE: 212-262--6 MAIL ADDRESS: STREET 1: 888 SEVENTH AVE STREET 2: 33RD FLR CITY: NEW YORK STATE: NY ZIP: 10106 SC 13D/A 1 sc13da4-viropharma.txt AMENDMENT NO. 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (AMENDMENT NO. 4) VIROPHARMA INCORPORATED (Name of Issuer) COMMON STOCK, PAR VALUE $.002 PER SHARE (Title of Class of Securities) 928241108 (CUSIP Number) KENNETH M. SOCHA, ESQ. PSV, LP 2099 PENNSYLVANIA AVENUE, N.W. SUITE 900 WASHINGTON, D.C. 20006-1813 TEL. NO.: (202) 452-0101 (Name, Address and Telephone Number of Person Authorized to Receive Notices and Communications) with a copy to BRUCE A. GUTENPLAN, ESQ. PAUL, WEISS, RIFKIND, WHARTON & GARRISON 1285 AVENUE OF THE AMERICAS NEW YORK, NEW YORK 10019-6064 OCTOBER 29, 2001 (Date of Event which Requires Filing of this Statement) If the filing person has previously filed a statement on Schedule 13G to report the acquisition which is the subject to this Schedule 13D, and is filing this schedule because of Rule 13d-1(b)(3) or (4), check the following box [_]. *The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter disclosures provided in a prior cover page. The information required on the remainder of this cover page shall not be deemed to be "filed" for the purposes of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes.) CUSIP NO. 98241108 PAGE 2 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON PSV, LP -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,518,146 (1) SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 0 EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,518,146 (1) WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 0 -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 (1) -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* PN -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Includes Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 3 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON PSV GP, LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,518,146 (1) SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 0 EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,518,146 (1) WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 0 -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 (1) -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Includes Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 4 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON PSV Partners, LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 0 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 595,000 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 0 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 595,000 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 595,000 (1) -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 3.1% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 5 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON SFM Participation, L.P. -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 923,146 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 595,000 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 923,146 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 595,000 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* PN -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 6 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON SFM AH, Inc. -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 923,146 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 595,000 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 923,146 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 595,000 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* CO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 7 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Rappahannock Investment Company -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION United States -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,152,646 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 834,397 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,152,646 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 834,397 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,987,043 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 10.3% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* CO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 8 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Frank H. Pearl (in the capacity described herein) -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION United States -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,152,646 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 834,397 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,152,646 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 834,397 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,987,043 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 10.3% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* IN -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 9 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON George Soros (in the capacity described herein) -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION United States -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 923,146 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 595,000 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 923,146 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 595,000 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* IA -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 10 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Soros Fund Management LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 923,146 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 595,000 (1) EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 923,146 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 595,000 (1) -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,518,146 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.9% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO; IA -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT ------------------------ 1/ Represents Warrant to purchase an aggregate of 595,000 shares of Common Stock. CUSIP NO. 98241108 PAGE 11 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Perseus Capital, LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,152,646 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 0 EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,152,646 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 0 -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,152,646 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 6.2% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT CUSIP NO. 98241108 PAGE 12 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Perseus Management, LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,152,646 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 0 EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,152,646 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 0 -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,152,646 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 6.2% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT CUSIP NO. 98241108 PAGE 13 OF 20 SCHEDULE 13D -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON Perseus, LLC -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) [_] (b) [X] -------------------------------------------------------------------------------- 3 SEC USE ONLY -------------------------------------------------------------------------------- 4 SOURCE OF FUNDS* Not Applicable -------------------------------------------------------------------------------- 5 CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E) [_] -------------------------------------------------------------------------------- 6 CITIZENSHIP OR PLACE OR ORGANIZATION Delaware -------------------------------------------------------------------------------- 7 SOLE VOTING POWER NUMBER OF 1,152,646 SHARES -------------------------------------------- BENEFICIALLY 8 SHARED VOTING POWER OWNED BY 239,397 EACH -------------------------------------------- REPORTING 9 SOLE DISPOSITIVE POWER PERSON 1,152,646 WITH -------------------------------------------- 10 SHARED DISPOSITIVE POWER 239,397 -------------------------------------------------------------------------------- 11 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,392,043 -------------------------------------------------------------------------------- 12 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES* [X] -------------------------------------------------------------------------------- 13 PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11) 7.4% -------------------------------------------------------------------------------- 14 TYPE OF REPORTING PERSON* OO -------------------------------------------------------------------------------- * SEE INSTRUCTIONS BEFORE FILLING OUT CUSIP NO. 98241108 PAGE 14 OF 20 This Amendment No. 4 ("Amendment No. 4") to Schedule 13D is filed by the undersigned to amend and supplement the Schedule 13D filed on May 17, 1999 (the "Original 13D"), as amended by Amendment No. 1 to the Schedule 13D filed on July 1, 2000 (the "Amendment No. 1"), as amended by Amendment No. 2 to the Schedule 13D filed on May 17, 2001 ("Amendment No. 2"), as amended by Amendment No. 3 to the Schedule 13D filed on September 17, 2001 ("Amendment No. 3") relating to the common stock (the "Common Stock"), par value $.002 per share, issued by ViroPharma Incorporated, a Delaware corporation (the "Company"). Unless otherwise indicated, all capitalized terms shall have the same meaning as provided in the Original 13D. ITEM 1. SECURITY AND ISSUER. No Change. ITEM 2. IDENTITY AND BACKGROUND. No change. ITEM 3. SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION. No change. ITEM 4. PURPOSE OF TRANSACTION. Item 4 is hereby amended and supplemented as follows: As discussed below in Item 5(c), each of the Purchaser and Perseus Capital sold an aggregate of 250,000 and 20,500 shares of Common Stock, respectively, pursuant to Rule 144 under the Securities Act of 1933, as amended (the "Securities Act"). Without limiting the disclosure set forth elsewhere herein, Perseus Capital currently intends to sell shares in an amount sufficient to realize cash proceeds approximately equal to its aggregate original investment in the Common Stock. The disclosure under the caption "Additional Disclosure" in Item 4 is hereby amended and restated in its entirety as follows: ADDITIONAL DISCLOSURE In accordance with Section 8.2 of the Investment Agreement, the Purchaser made a written request that the Company file a registration statement (the "Registration Statement") for an offering to be made on a continuous basis pursuant to Rule 415 of the Securities Act registering the resale from time to time of a portion of the Common Stock it beneficially owns and the Common Stock issuable upon exercise of the Warrants. The Registration Statement was declared effective by Securities and CUSIP NO. 98241108 PAGE 15 OF 20 Exchange Commission on October 19, 2001. The Reporting Persons may from time to time sell all or a portion the Common Stock, Warrant, or Common Stock issued upon exercise of the Warrant in privately negotiated transactions or in the open market pursuant to the Registration Statement or other exercise of their registration rights or Rule 144, in each case, subject to prices for the Common Stock deemed favorable by the Reporting Persons, the Company's business or financial condition and other factors and conditions the Reporting Persons deem appropriate and to the terms of the Investment Agreement and the Warrant, as the case may be. Alternatively, the Reporting Persons may from time to time acquire additional shares of Common Stock in privately negotiated transactions or in the open market, in each case, subject to availability of Common Stock at prices deemed favorable, the Company's business or financial condition and other factors and conditions the Reporting Persons deem appropriate. In addition, the Reporting Persons may formulate other purposes, plans or proposals regarding the Company or any of its securities to the extent deemed advisable in light of general investment and trading policies, market conditions or other factors. Except as described in the Investment Agreement or the Warrant, and as otherwise set forth in the Original 13D or any amendment thereto, including this Amendment No. 4, no Reporting Person or any individual otherwise identified in Item 2 has any present plans or proposals which relate to or would result in any of the events described in Items (a) through (j) of Item 4 of Schedule 13D. ITEM 5. INTEREST IN SECURITIES OF THE ISSUER. Item 5 is hereby amended and restated in its entirety as follows: (a) As of the date hereof: (i) each of the Purchaser, PSV GP, SFM Participation, SFM AH, Mr. Soros and SFM LLC may be deemed to beneficially own an aggregate of 1,518,146 shares of Common Stock which, based on calculations made in accordance with Rule 13d-3(d) and there being 18,699,695 shares of Common Stock outstanding as of August 31, 2001 as disclosed by the Company in its Amendment No. 2 to the Registration Statement on Form S-3 as filed with the Securities and Exchange Commission on October 10, 2001, represents approximately 7.9% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d); (ii) each of Rappahannock and Mr. Pearl may be deemed to beneficially own an aggregate of 1,987,043 shares of Common Stock (which includes the shares held by Perseus Capital and the Warrants held by the Purchaser and an additional 239,397 shares of Common Stock beneficially owned by New York Life BioVenture Partners LLC, a Delaware limited CUSIP NO. 98241108 PAGE 16 OF 20 liability company ("New York Life"), as more fully discussed below) which, based on calculations made in accordance with Rule 13d-3(d) and there being 18,699,695 shares of Common Stock outstanding as of August 31, 2001 as disclosed by the Company in its Amendment No. 2 to the Registration Statement on Form S-3 as filed with the Securities and Exchange Commission on October 10, 2001, represents approximately 10.3% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d); (iii) Perseus may be deemed to beneficially own an aggregate of 1,392,043 shares of Common Stock (which includes the shares held by Perseus Capital and an additional 239,397 shares of Common Stock beneficially owned by New York Life, as more fully discussed below) which, based on calculations made in accordance with Rule 13d-3(d) and there being 18,699,695 shares of Common Stock outstanding as of August 31, 2001 as disclosed by the Company in its Amendment No. 2 to the Registration Statement on Form S-3 as filed with the Securities and Exchange Commission on October 10, 2001, represents approximately 7.4% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d); (iv) each of Perseus Capital and Perseus Management may be deemed to beneficially own an aggregate of 1,152,646 shares of Common Stock which, based on calculations made in accordance with Rule 13d-3(d) and there being 18,699,695 shares of Common Stock outstanding as of August 31, 2001 as disclosed by the Company in its Amendment No. 2 to the Registration Statement on Form S-3 as filed with the Securities and Exchange Commission on October 10, 2001, represents approximately 6.2% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d); and (v) PSV Partners may be deemed to beneficially own an aggregate of 595,000 shares of Common Stock which, based on calculations made in accordance with Rule 13d-3(d) and there being 18,699,695 shares of Common Stock outstanding as of August 31, 2001 as disclosed by the Company in its Amendment No. 2 to the Registration Statement on Form S-3 as filed with the Securities and Exchange Commission on October 10, 2001, represents approximately 3.1% of the outstanding shares of Common Stock on a diluted basis in accordance with Rule 13d-3(d). As noted above, Perseus, Rappahannock and Mr. Pearl may be deemed to beneficially own the 239,397 shares of Common Stock owned by New York Life. Mr. Pearl is the sole shareholder of Rappahannock, which is the sole member of Perseus, a member of Perseus Biotech Advisors, LLC ("Perseus Biotech Advisors"). Pursuant to a management agreement executed on August 1, 2000 (the "Management Agreement"), New York Life Investment Management, LLC, the sole manager of New York Life, retained Perseus Biotech Advisors to act as investment manager CUSIP NO. 98241108 PAGE 17 OF 20 of New York Life. The Management Agreement is a general agreement pursuant to which Perseus Biotech Advisors became the investment manager of New York Life with respect to its portfolio companies. Prior to August 1, 2000, New York Life acquired 239,397 shares of Common Stock. As a result of the Management Agreement, Perseus, Rappahannock and Mr. Pearl may be deemed to beneficially own the 239,397 shares of Common Stock owned by New York Life. (b) (i) Each of the Purchaser and PSV GP may be deemed to have sole power to direct the voting and disposition of the 1,518,146 shares of Common Stock beneficially owned by the Purchaser. With respect to the 923,146 shares of Common Stock beneficially owned by the Purchaser, each of SFM Participation, SFM AH, Mr. Soros and SFM LLC may be deemed to have sole power to direct the voting and disposition of such shares. With respect to the 1,152,646 shares of Common Stock beneficially owned by Perseus Capital, each of Perseus Management, Perseus, Rappahannock and Mr. Pearl may be deemed to have the sole power to direct the voting and disposition of such shares. (ii) By virtue of the relationships between and among the Reporting Persons, each of PSV Partners, SFM Participation, SFM AH, Rappahannock, Mr. Pearl, Mr. Soros and SFM LLC may be deemed to share the power to direct the voting and disposition of the 595,000 shares of Common Stock issuable upon exercise of the Warrant beneficially owned by the Purchaser. (iii) Perseus, Rappahannock and Mr. Pearl may be deemed to share the power to direct the voting and disposition of the 239,397 shares of Common Stock owned by New York Life. Each of the Reporting Persons, other than Perseus, Rappahannock and Mr. Pearl, disclaim beneficial ownership of the 239,397 shares of Common Stock owned by New York Life. (c) Between October 10, 2001 and October 31, 2001, each of the Purchaser and Perseus Capital sold the following number of shares under Rule 144 on the dates and for the prices set forth below: CUSIP NO. 98241108 PAGE 18 OF 20 PURCHASER DATE SHARES SOLD PRICE ---- ----------- ----- 10/10/01 28,000 $29.08 10/11/01 8,800 28.97 10/12/01 37,500 28.00 10/15/01 55,500 28.08 10/16/01 16,000 27.99 10/17/01 2,000 27.89 10/26/01 30,500 26.24 10/29/01 44,500 25.08 10/31/01 23,200 25.00 10/31/01 4,000 25.00 PERSEUS DATE SHARES SOLD PRICE PER SHARE ---- ----------- --------------- 10/11/2001 12,000 $28.89 10/12/2001 600 28.00 10/15/2001 1,400 28.90 10/18/2001 500 27.50 10/19/2001 2,000 27.50 10/23/2001 4,000 27.53 All such sales were made in the open market. (d) Each of the Reporting Persons affirms that, except as set forth below, no person other than the Reporting Persons has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the shares of Common Stock owned by the Reporting Persons. The partners of the Purchaser and the members of Perseus Capital have the right to participate in the receipt of dividends from, or proceeds from the sale of, the Securities held for the account of each of the Purchaser and Perseus Capital in accordance with their ownership interests in each of the Purchaser and Perseus Capital. (e) No change. ITEM 6. CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH RESPECT TO SECURITIES OF THE ISSUER. No change. ITEM 7. MATERIAL TO BE FILED AS EXHIBITS. Exhibit 1: Incorporate by reference the Power of Attorney, filed as Exhibit 2 to Amendment No. 1 to the Schedule 13D, appointing Richard D. Holahan, Jr., Attorney-In-Fact for George Soros. CUSIP NO. 98241108 PAGE 19 OF 20 SIGNATURE After reasonable inquiry and to the best of its knowledge and belief, each of the undersigned certifies that the information set forth in this statement is true, complete and correct. Dated: November 2, 2001 PSV, LP By: PSV GP, LLC, General Partner By: SFM Participation, L.P., Member By: SFM AH, Inc., General Partner By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Secretary PSV GP, LLC By: SFM Participation, L.P., Member By: SFM AH, Inc., General Partner By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Secretary PSV PARTNERS, LLC By: Rappahannock Investment Company, Managing Member By: /s/ Frank H. Pearl --------------------------------------- Name: Frank H. Pearl Title: Sole Shareholder RAPPAHANNOCK INVESTMENT COMPANY By: /s/ Frank H. Pearl --------------------------------------- Name: Frank H. Pearl Title: Sole Shareholder MR. FRANK H. PEARL By: /s/ Frank H. Pearl --------------------------------------- Name: Frank H. Pearl CUSIP NO. 98241108 PAGE 20 OF 20 SFM PARTICIPATION, L.P. By: SFM AH, Inc., General Partner By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Secretary SFM AH, INC. By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Secretary MR. GEORGE SOROS By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Attorney-in-fact SOROS FUND MANAGEMENT LLC By: /s/ Richard D. Holahan, Jr. --------------------------------------- Name: Richard D. Holahan, Jr. Title: Assistant General Counsel PERSEUS CAPITAL, LLC By: /s/ Kenneth M. Socha --------------------------------------- Name: Kenneth M. Socha Title: Executive Vice President PERSEUS MANAGEMENT, LLC By: /s/ Kenneth M. Socha --------------------------------------- Name: Kenneth M. Socha Title: Executive Vice President PERSEUS, LLC By: /s/ Kenneth M. Socha --------------------------------------- Name: Kenneth M. Socha Title: Executive Vice President